BAIT
PRKCD
AI385711, D14Ertd420e, PKC[d], PKCdelta, Pkcd
protein kinase C, delta
GO Process (35)
GO Function (8)
GO Component (10)
Gene Ontology Biological Process
- B cell proliferation [IMP]
- apoptotic process [ISO]
- aspartate transport [ISO]
- cellular senescence [ISO]
- collagen metabolic process [ISO]
- defense response to bacterium [IMP]
- immunoglobulin mediated immune response [IMP]
- interleukin-10 production [IMP]
- interleukin-12 production [IMP]
- intracellular signal transduction [ISO]
- negative regulation of MAP kinase activity [ISO]
- negative regulation of actin filament polymerization [IMP]
- negative regulation of filopodium assembly [IMP]
- negative regulation of glial cell apoptotic process [ISO]
- negative regulation of insulin receptor signaling pathway [IMP]
- negative regulation of peptidyl-tyrosine phosphorylation [IMP]
- negative regulation of platelet aggregation [IMP]
- neutrophil activation [ISO]
- peptidyl-threonine phosphorylation [ISO]
- positive regulation of MAP kinase activity [ISO]
- positive regulation of MAPK cascade [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of apoptotic signaling pathway [IDA]
- positive regulation of ceramide biosynthetic process [ISO]
- positive regulation of glucose import [ISO]
- positive regulation of glucosylceramide catabolic process [ISO]
- positive regulation of phospholipid scramblase activity [ISO]
- positive regulation of protein dephosphorylation [ISO]
- positive regulation of response to DNA damage stimulus [ISO]
- positive regulation of sphingomyelin catabolic process [ISO]
- positive regulation of superoxide anion generation [ISO]
- protein autophosphorylation [ISO]
- protein phosphorylation [IDA, ISO]
- response to oxidative stress [ISO]
- termination of signal transduction [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PDP1
Gm1024, Ppm2c, RP23-203A12.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
GO Process (2)
GO Function (6)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- mitochondrion [IDA, ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.819 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID