BAIT
CEP76
6230425F05Rik, 9630013E05
centrosomal protein 76
GO Process (1)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Mus musculus
PREY
PLCB1
3110043I21Rik, AI132408, Plcb, mKIAA0581, RP23-418D21.3
phospholipase C, beta 1
GO Process (36)
GO Function (9)
GO Component (8)
Gene Ontology Biological Process
- G-protein coupled acetylcholine receptor signaling pathway [IMP]
- G2/M transition of mitotic cell cycle [IDA, NAS]
- activation of meiosis involved in egg activation [IDA]
- brain development [NAS]
- cell adhesion [IC]
- cerebral cortex development [IMP]
- erythrocyte differentiation [TAS]
- fat cell differentiation [IDA]
- glutamate receptor signaling pathway [IMP]
- insulin receptor signaling pathway [TAS]
- insulin-like growth factor receptor signaling pathway [IDA]
- interleukin-1-mediated signaling pathway [ISO]
- interleukin-12-mediated signaling pathway [ISO]
- interleukin-15-mediated signaling pathway [ISO]
- mRNA processing [TAS]
- macrophage differentiation [NAS]
- memory [IMP]
- negative regulation of monocyte extravasation [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- oocyte maturation [NAS]
- positive regulation of CD24 biosynthetic process [IDA]
- positive regulation of G1/S transition of mitotic cell cycle [IDA]
- positive regulation of GTPase activity [ISO]
- positive regulation of JNK cascade [ISO]
- positive regulation of acrosome reaction [IMP]
- positive regulation of developmental growth [IMP]
- positive regulation of embryonic development [IMP]
- positive regulation of interleukin-12 production [IMP]
- positive regulation of myoblast differentiation [IDA]
- positive regulation of sodium:proton antiporter activity [NAS]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of G-protein coupled receptor protein signaling pathway [IMP]
- regulation of fertilization [IMP]
- response to monosaccharide [ISO]
- response to peptide hormone [ISO]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.7845 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID