BAIT
CRKL
1110025F07Rik, AA589403, AI325100, Crkol
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
GO Process (7)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PLEKHA1
AA960558, C920009D07Rik, TAPP1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
GO Process (18)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- B cell receptor signaling pathway [ISO]
- Leydig cell differentiation [IMP]
- androgen metabolic process [IMP]
- cellular response to hydrogen peroxide [ISO]
- establishment of protein localization [ISO]
- estrogen metabolic process [IGI]
- face morphogenesis [IMP]
- female gonad development [IGI]
- luteinization [IGI]
- multicellular organism growth [IMP]
- negative regulation of protein kinase B signaling [ISO]
- palate development [IMP]
- phosphatidylinositol 3-kinase signaling [ISO]
- platelet-derived growth factor receptor signaling pathway [IMP]
- post-embryonic development [IMP]
- ruffle organization [ISO]
- skeletal system morphogenesis [IMP]
- spermatogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.753 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID