BAIT
EIF4A3
2400003O03Rik, Ddx48, eIF4A-III, mKIAA0111, RP23-13O17.1
eukaryotic translation initiation factor 4A3
GO Process (7)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- embryonic cranial skeleton morphogenesis [ISO]
- negative regulation of translation [ISO]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [ISO]
- positive regulation of mRNA splicing, via spliceosome [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of translation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PRMT1
6720434D09Rik, AW214366, Hrmt1l2, Mrmt1
protein arginine N-methyltransferase 1
GO Process (11)
GO Function (13)
GO Component (3)
Gene Ontology Biological Process
- histone H4-R3 methylation [IBA, ISO]
- histone methylation [IDA, ISO]
- in utero embryonic development [IMP]
- negative regulation of megakaryocyte differentiation [ISO]
- neuron projection development [ISO]
- peptidyl-arginine N-methylation [IDA]
- peptidyl-arginine methylation [ISO]
- peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [IBA, ISO]
- peptidyl-arginine omega-N-methylation [ISO]
- protein methylation [IMP, ISO]
- regulation of transcription, DNA-templated [IBA]
Gene Ontology Molecular Function- N-methyltransferase activity [ISO]
- [cytochrome c]-arginine N-methyltransferase activity [ISO]
- histone methyltransferase activity [IDA, ISO]
- histone methyltransferase activity (H4-R3 specific) [IBA, ISO]
- histone-arginine N-methyltransferase activity [ISO]
- identical protein binding [ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein methyltransferase activity [IMP, ISO]
- protein-arginine N-methyltransferase activity [IDA, ISO]
- protein-arginine omega-N asymmetric methyltransferase activity [IBA, ISO]
- protein-arginine omega-N monomethyltransferase activity [ISO]
- snoRNP binding [ISO]
- N-methyltransferase activity [ISO]
- [cytochrome c]-arginine N-methyltransferase activity [ISO]
- histone methyltransferase activity [IDA, ISO]
- histone methyltransferase activity (H4-R3 specific) [IBA, ISO]
- histone-arginine N-methyltransferase activity [ISO]
- identical protein binding [ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein methyltransferase activity [IMP, ISO]
- protein-arginine N-methyltransferase activity [IDA, ISO]
- protein-arginine omega-N asymmetric methyltransferase activity [IBA, ISO]
- protein-arginine omega-N monomethyltransferase activity [ISO]
- snoRNP binding [ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.777 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID