BAIT
SYP
A230093K24Rik, AI848995, Syn, p38, RP23-54C14.4
synaptophysin
GO Process (6)
GO Function (7)
GO Component (13)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- excitatory synapse [IDA, ISO]
- integral component of synaptic vesicle membrane [IBA, TAS]
- intracellular organelle [ISO]
- membrane [IDA]
- neuron projection [ISO]
- neuron projection terminus [IDA, ISO]
- presynaptic active zone [IDA, ISO]
- presynaptic membrane [IDA]
- protein complex [ISO]
- synapse [IDA]
- synaptic vesicle [IDA, ISO]
- synaptic vesicle membrane [IDA]
- terminal bouton [ISO]
Mus musculus
PREY
SRCIN1
P140, SNIP, mKIAA1684, p140Cap, RP23-157O10.7
SRC kinase signaling inhibitor 1
GO Process (7)
GO Function (3)
GO Component (12)
Gene Ontology Biological Process
- negative regulation of cell adhesion [IDA]
- negative regulation of protein secretion [ISO]
- negative regulation of protein tyrosine kinase activity [ISO]
- positive regulation of protein tyrosine kinase activity [ISO]
- regulation of cell migration [ISO]
- regulation of dendritic spine morphogenesis [ISO]
- substrate adhesion-dependent cell spreading [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.7735 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID