BAIT
ANXA11
A830099O17Rik, Anx11
annexin A11
GO Process (2)
GO Function (7)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SRI
2210417O06Rik, 2900070H08Rik, Sor
sorcin
GO Process (13)
GO Function (6)
GO Component (18)
Gene Ontology Biological Process
- calcium ion transport [IPI]
- cytoplasmic sequestering of transcription factor [IMP]
- negative regulation of heart rate [ISO]
- negative regulation of ryanodine-sensitive calcium-release channel activity [ISO]
- negative regulation of transcription regulatory region DNA binding [IMP]
- positive regulation of insulin secretion involved in cellular response to glucose stimulus [IMP]
- positive regulation of release of sequestered calcium ion into cytosol [IMP]
- proteolysis [IBA]
- regulation of calcium ion transport [ISO]
- regulation of cardiac muscle cell contraction [ISO]
- regulation of cell communication by electrical coupling involved in cardiac conduction [ISO]
- regulation of high voltage-gated calcium channel activity [ISO]
- regulation of relaxation of muscle [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- T-tubule [ISO]
- Z disc [IDA, ISO]
- axon [ISO]
- axon terminus [ISO]
- cell [IMP]
- chromaffin granule membrane [ISO]
- cytoplasm [IMP, ISO]
- cytosol [ISO]
- dendritic spine neck [ISO]
- endoplasmic reticulum membrane [ISO]
- extracellular vesicular exosome [ISO]
- intracellular [IDA]
- membrane [ISO]
- mitochondrion [ISO]
- nucleoplasm [ISO]
- plasma membrane [IDA, ISO]
- smooth endoplasmic reticulum [ISO]
- vesicle [IDA]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.7485 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID