BAIT
FBXO22
0610033L19Rik, 1600016C16Rik
F-box protein 22
GO Process (7)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- cellular response to starvation [IDA]
- nucleocytoplasmic transport [IDA]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IMP]
- protein polyubiquitination [IDA]
- regulation of myotube differentiation [IMP]
- regulation of skeletal muscle fiber development [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
SRR
Srs, RP23-174M12.5
serine racemase
GO Process (7)
GO Function (12)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function- ATP binding [IDA, ISO]
- D-serine ammonia-lyase activity [IBA]
- L-serine ammonia-lyase activity [IBA, ISO]
- PDZ domain binding [ISO]
- calcium ion binding [IDA]
- glycine binding [IDA]
- magnesium ion binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [IDA, ISO]
- pyridoxal phosphate binding [IMP, ISO]
- serine racemase activity [IDA, ISO]
- threonine racemase activity [IDA]
- ATP binding [IDA, ISO]
- D-serine ammonia-lyase activity [IBA]
- L-serine ammonia-lyase activity [IBA, ISO]
- PDZ domain binding [ISO]
- calcium ion binding [IDA]
- glycine binding [IDA]
- magnesium ion binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [IDA, ISO]
- pyridoxal phosphate binding [IMP, ISO]
- serine racemase activity [IDA, ISO]
- threonine racemase activity [IDA]
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.7995 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID