BAIT
PNP
AL024301, AU015798, Np, Np-1, Np-2, Pnp1
purine-nucleoside phosphorylase
GO Process (17)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- GTP biosynthetic process [IMP]
- apoptotic mitochondrial changes [IMP]
- dGTP metabolic process [IMP]
- deoxyguanosine catabolic process [IMP]
- deoxyinosine catabolic process [IMP]
- guanosine catabolic process [IMP]
- inosine catabolic process [IMP, ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage [IMP]
- negative regulation of T cell apoptotic process [IMP]
- positive regulation of B cell differentiation [IMP]
- positive regulation of DNA repair [IMP]
- positive regulation of T cell mediated cytotoxicity [IMP]
- positive regulation of T cell proliferation [IMP, ISO]
- positive regulation of alpha-beta T cell differentiation [IMP, ISO]
- purine nucleoside metabolic process [IC, IDA, IMP]
- response to gamma radiation [IMP]
- urate biosynthetic process [IMP, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
TFAM
AI661103, Hmgts, mtTFA, tsHMG
transcription factor A, mitochondrial
GO Process (7)
GO Function (8)
GO Component (4)
Gene Ontology Biological Process
- chromatin remodeling [IBA]
- mitochondrial respiratory chain complex assembly [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of transcription, DNA-templated [IBA, TAS]
- transcription from mitochondrial promoter [ISO]
- transcription initiation from mitochondrial promoter [ISO]
Gene Ontology Molecular Function- DNA binding [ISO]
- DNA binding, bending [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- chromatin binding [IBA, ISO]
- heat shock protein binding [ISO]
- mitochondrial light strand promoter sense binding [ISO]
- poly(A) RNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO, TAS]
- DNA binding [ISO]
- DNA binding, bending [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- chromatin binding [IBA, ISO]
- heat shock protein binding [ISO]
- mitochondrial light strand promoter sense binding [ISO]
- poly(A) RNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO, TAS]
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.693 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID