BAIT
TCP1
AI528772, CCT, Cct1, Ccta, TRic, Tcp-1, Tp63, c-cpn, p63, RP23-351C7.3
t-complex protein 1
GO Process (4)
GO Function (3)
GO Component (13)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- acrosomal vesicle [IDA]
- cell body [IDA]
- centrosome [ISO]
- chaperonin-containing T-complex [IDA]
- extracellular vesicular exosome [ISO]
- heterochromatin [ISO]
- microtubule [ISO]
- microtubule organizing center [IDA]
- myelin sheath [IDA]
- nuclear heterochromatin [IDA]
- pericentriolar material [IDA]
- zona pellucida receptor complex [IDA]
Mus musculus
PREY
USP9X
5730589N07Rik, AA407302, AA407699, AL022658, AL022749, Dffrx, FAF-X, Fafl, RP23-216M21.1
ubiquitin specific peptidase 9, X chromosome
GO Process (13)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- BMP signaling pathway [ISO]
- axon extension [IMP, ISO]
- cellular response to transforming growth factor beta stimulus [IMP]
- cerebellar cortex structural organization [IMP]
- hippocampus development [IMP]
- in utero embryonic development [IGI]
- neuron migration [IMP, ISO]
- neuron projection extension [IGI]
- post-embryonic development [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA]
- protein deubiquitination [IBA, ISO]
- regulation of proteasomal protein catabolic process [IBA]
- transforming growth factor beta receptor signaling pathway [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.806 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID