NAPB
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
VAMP2
Gene Ontology Biological Process
- Golgi to plasma membrane protein transport [IMP]
- calcium ion-dependent exocytosis [IDA, IMP]
- cellular response to insulin stimulus [IDA]
- eosinophil degranulation [ISO]
- long-term synaptic potentiation [IMP]
- membrane fusion [IMP]
- positive regulation of intracellular protein transport [IMP]
- protein complex assembly [ISO]
- protein transport [ISO]
- regulation of exocytosis [IDA, ISO]
- regulation of vesicle-mediated transport [IMP]
- response to glucose [ISO]
- synaptic vesicle exocytosis [IMP]
- vesicle fusion [IBA]
- vesicle-mediated transport [ISO]
Gene Ontology Molecular Function- SNAP receptor activity [IBA]
- SNARE binding [IDA, ISO]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- identical protein binding [ISO]
- myosin binding [ISO]
- phospholipid binding [IDA]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- syntaxin binding [IPI, ISO]
- syntaxin-1 binding [ISO]
- SNAP receptor activity [IBA]
- SNARE binding [IDA, ISO]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- identical protein binding [ISO]
- myosin binding [ISO]
- phospholipid binding [IDA]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- syntaxin binding [IPI, ISO]
- syntaxin-1 binding [ISO]
Gene Ontology Cellular Component
- SNARE complex [ISO]
- cell [IMP]
- clathrin-coated vesicle [ISO]
- cytoplasmic vesicle [IDA]
- extracellular vesicular exosome [ISO]
- intracellular [IMP]
- intracellular membrane-bounded organelle [ISO]
- intracellular organelle [ISO]
- membrane [ISO]
- neuron projection [ISO]
- neuron projection terminus [ISO]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA, ISO]
- secretory granule [IDA, ISO]
- synapse [IDA]
- synaptic vesicle [IDA, ISO]
- synaptic vesicle membrane [IDA]
- synaptobrevin 2-SNAP-25-syntaxin-1a complex [IDA, ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex [ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex [ISO]
- terminal bouton [ISO]
- trans-Golgi network [IDA]
- zymogen granule membrane [IDA]
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Quantitative Score
- 0.9775 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| VAMP2 NAPB | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - |
Curated By
- BioGRID