BAIT
GSK3A
2700086H06Rik
glycogen synthase kinase 3 alpha
GO Process (26)
GO Function (4)
GO Component (0)
Gene Ontology Biological Process
- cardiac left ventricle morphogenesis [IMP]
- cell migration [IGI]
- cellular response to insulin stimulus [ISO]
- cellular response to interleukin-3 [IDA]
- cellular response to lithium ion [IDA]
- cellular response to organic cyclic compound [IDA]
- extrinsic apoptotic signaling pathway in absence of ligand [IDA]
- hypermethylation of CpG island [IMP]
- insulin receptor signaling pathway [IDA]
- negative regulation of TOR signaling [IMP]
- negative regulation of cell growth involved in cardiac muscle cell development [IMP]
- negative regulation of glucose import [ISO]
- negative regulation of insulin receptor signaling pathway [ISO]
- negative regulation of transferase activity [ISO]
- positive regulation of adrenergic receptor signaling pathway [IMP]
- positive regulation of cAMP biosynthetic process [IMP]
- positive regulation of glycogen (starch) synthase activity [IMP]
- positive regulation of heart contraction [IMP]
- positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [IDA]
- positive regulation of peptidyl-serine phosphorylation [IDA]
- positive regulation of peptidyl-threonine phosphorylation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IDA]
- protein phosphorylation [IDA, IMP, ISO]
- regulation of gene expression by genetic imprinting [IMP]
- regulation of systemic arterial blood pressure [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
VTA1
1110001D18Rik, 1110059P08Rik, AU040813, C85340, LIP5, SBP1
Vps20-associated 1 homolog (S. cerevisiae)
GO Process (0)
GO Function (1)
GO Component (2)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.7345 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID