BAIT
USP46
1190009E20Rik, 2410018I08Rik, AI451644
ubiquitin specific peptidase 46
GO Process (7)
GO Function (2)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
WDR48
8430408H12Rik, Uaf1, mKIAA1449
WD repeat domain 48
GO Process (14)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [IMP]
- double-strand break repair via homologous recombination [IMP]
- embryonic organ development [IMP]
- homeostasis of number of cells [IMP]
- male gonad development [IMP]
- multicellular organism growth [IMP]
- positive regulation of epithelial cell proliferation [IMP]
- protein deubiquitination [ISO]
- regulation of protein monoubiquitination [IMP]
- seminiferous tubule development [IMP]
- single fertilization [IMP]
- skeletal system morphogenesis [IMP]
- skin development [IMP]
- spermatogenesis [IMP]
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.9095 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID