BAIT
GAPDH
Gapd
glyceraldehyde-3-phosphate dehydrogenase
GO Process (13)
GO Function (4)
GO Component (14)
Gene Ontology Biological Process
- apoptotic process [ISO]
- carbohydrate metabolic process [ISO]
- cellular response to interferon-gamma [ISO]
- gluconeogenesis [ISO]
- glycolytic process [ISO]
- microtubule cytoskeleton organization [ISO]
- multicellular organismal development [IMP]
- negative regulation of translation [ISO]
- neuron apoptotic process [ISO]
- oxidation-reduction process [IMP]
- peptidyl-cysteine S-trans-nitrosylation [ISO]
- protein stabilization [ISO]
- response to ammonium ion [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- GAIT complex [IDA, ISO]
- cytoplasm [IDA, ISO]
- cytosol [IDA, ISO]
- extracellular vesicular exosome [ISO]
- intracellular membrane-bounded organelle [ISO]
- lipid particle [ISO]
- membrane [ISO]
- microtubule cytoskeleton [ISO]
- mitochondrion [IDA]
- nuclear membrane [ISO]
- nucleus [ISO]
- plasma membrane [ISO]
- ribonucleoprotein complex [ISO]
- vesicle [ISO]
Mus musculus
PREY
YBX1
1700102N10Rik, C79409, EF1A, MSY1, Nsep1, YB-1, dbpB, mYB-1a, RP24-363D14.2
Y box protein 1
GO Process (10)
GO Function (12)
GO Component (12)
Gene Ontology Biological Process
- CRD-mediated mRNA stabilization [ISO]
- in utero embryonic development [IGI, IMP]
- negative regulation of apoptotic process [ISO]
- negative regulation of insulin receptor signaling pathway [ISO]
- negative regulation of striated muscle cell differentiation [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI, ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- regulation of transcription, DNA-templated [ISO]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function- DNA binding [ISO]
- RNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- chromatin binding [IDA]
- mRNA binding [ISO]
- p53 binding [ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding [ISO]
- single-stranded DNA binding [IDA, ISO]
- transcription factor binding [ISO]
- DNA binding [ISO]
- RNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- chromatin binding [IDA]
- mRNA binding [ISO]
- p53 binding [ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding [ISO]
- single-stranded DNA binding [IDA, ISO]
- transcription factor binding [ISO]
Gene Ontology Cellular Component
- CRD-mediated mRNA stability complex [ISO]
- U12-type spliceosomal complex [ISO]
- cytoplasm [IDA, ISO]
- cytoplasmic stress granule [ISO]
- dendrite [ISO]
- extracellular vesicular exosome [ISO]
- histone pre-mRNA 3'end processing complex [IDA]
- intracellular membrane-bounded organelle [ISO]
- nuclear membrane [ISO]
- nucleus [IGI, ISO]
- perinuclear region of cytoplasm [ISO]
- ribonucleoprotein complex [ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.779 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID