BAIT
KANK2
AI504612, Ankrd25, BC010245
KN motif and ankyrin repeat domains 2
GO Process (6)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
- negative regulation of G1/S transition of mitotic cell cycle [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of intracellular estrogen receptor signaling pathway [ISO]
- negative regulation of programmed cell death [ISO]
- negative regulation of stress fiber assembly [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
ABI3
2210414K06Rik, AI987680, NESH, RP23-151M22.4
ABI gene family, member 3
GO Process (2)
GO Function (0)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.931 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID