BAIT
IFT122
C86139, Wdr10, sopb
intraflagellar transport 122
GO Process (21)
GO Function (0)
GO Component (9)
Gene Ontology Biological Process
- camera-type eye morphogenesis [IMP]
- ciliary receptor clustering involved in smoothened signaling pathway [IGI]
- cilium assembly [IBA]
- cilium morphogenesis [IGI, IMP]
- dorsal/ventral pattern formation [IGI, IMP]
- embryonic body morphogenesis [IMP]
- embryonic digit morphogenesis [IMP]
- embryonic forelimb morphogenesis [IMP]
- embryonic heart tube development [IMP]
- embryonic heart tube left/right pattern formation [IMP]
- establishment of protein localization to organelle [IMP]
- intraciliary anterograde transport [IMP]
- intraciliary retrograde transport [IMP]
- limb development [IMP]
- negative regulation of epithelial cell proliferation [IMP]
- negative regulation of smoothened signaling pathway [IMP]
- negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning [IMP]
- neural tube closure [IMP]
- protein localization to cilium [IBA, ISO]
- signal transduction downstream of smoothened [IMP]
- smoothened signaling pathway involved in dorsal/ventral neural tube patterning [IGI]
Gene Ontology Cellular Component
Mus musculus
PREY
AKAP9
5730481H23Rik, AKAP-9, AKAP450, AW545847, C79026, G1-448-15, PRKA9, mKIAA0803, mei2-5, repro12
A kinase (PRKA) anchor protein (yotiao) 9
GO Process (2)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.945 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID