BAIT
PDE4DIP
4732458A06Rik, 9430063L05Rik, C87016, D130016K21Rik, D3Bwg1078e, Usmg4, mKIAA0454
phosphodiesterase 4D interacting protein (myomegalin)
GO Process (1)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
ATP2A1
SERCA1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
GO Process (20)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- apoptotic mitochondrial changes [ISO]
- calcium ion import [ISO]
- calcium ion transmembrane transport [ISO]
- calcium ion transport [ISO]
- carbohydrate derivative transport [ISO]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [ISO]
- maintenance of mitochondrion location [ISO]
- negative regulation of endoplasmic reticulum calcium ion concentration [ISO]
- negative regulation of striated muscle contraction [ISO]
- nucleotide transmembrane transport [ISO]
- positive regulation of endoplasmic reticulum calcium ion concentration [ISO]
- positive regulation of fast-twitch skeletal muscle fiber contraction [ISO]
- positive regulation of mitochondrial calcium ion concentration [ISO]
- regulation of muscle contraction [TAS]
- regulation of striated muscle contraction [ISO]
- relaxation of skeletal muscle [ISO]
- response to endoplasmic reticulum stress [ISO]
- response to peptide hormone [ISO]
- sarcoplasmic reticulum calcium ion transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.716 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID