BAIT
KIF3C
mKIAA4058
kinesin family member 3C
GO Process (2)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
AURKA
AIRK1, ARK-1, AU019385, AW539821, Ark1, Aurora-A, Ayk1, IAK, IAK1, Stk6
aurora kinase A
GO Process (23)
GO Function (7)
GO Component (16)
Gene Ontology Biological Process
- anterior/posterior axis specification [IMP]
- centrosome localization [IMP]
- centrosome organization [IGI]
- histone-serine phosphorylation [IMP]
- meiotic nuclear division [IMP]
- meiotic spindle organization [IMP]
- microtubule cytoskeleton organization [IGI]
- mitotic cell cycle [IMP]
- mitotic centrosome separation [IGI, IMP]
- mitotic nuclear division [IMP]
- mitotic spindle organization [IMP]
- negative regulation of apoptotic process [IMP]
- negative regulation of protein binding [ISO]
- negative regulation of spindle checkpoint [IMP]
- neuron projection extension [IGI]
- positive regulation of oocyte maturation [IMP]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- protein localization to centrosome [IMP]
- protein phosphorylation [IBA, IGI, ISO]
- regulation of cytokinesis [IBA]
- regulation of protein stability [ISO]
- spindle assembly involved in female meiosis I [IMP]
- spindle stabilization [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon hillock [IDA]
- centrosome [IDA, ISO]
- chromosome passenger complex [IBA]
- condensed nuclear chromosome, centromeric region [IBA]
- germinal vesicle [IDA]
- meiotic spindle [IDA]
- microtubule cytoskeleton [ISO]
- microtubule organizing center [IGI]
- mitotic spindle [IDA]
- nucleus [ISO]
- perinuclear region of cytoplasm [ISO]
- pronucleus [IDA]
- spindle [ISO]
- spindle microtubule [IBA, ISO]
- spindle midzone [IBA]
- spindle pole centrosome [IBA, ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.76 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID