BAIT
SMARCA2
2610209L14Rik, SNF2alpha, Snf2l2, brahma, brm
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
GO Process (9)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- aortic smooth muscle cell differentiation [IMP]
- chromatin organization [TAS]
- negative regulation of cell growth [ISO]
- negative regulation of cell proliferation [IMP]
- negative regulation of transcription, DNA-templated [ISO]
- nucleosome assembly [TAS]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
BAZ1B
C87820, WSTF, Wbscr9
bromodomain adjacent to zinc finger domain, 1B
GO Process (10)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [ISO]
- chromatin assembly or disassembly [IDA]
- chromatin remodeling [IDA]
- chromatin-mediated maintenance of transcription [IMP]
- double-strand break repair [IMP]
- heart morphogenesis [IMP]
- histone phosphorylation [ISO]
- peptidyl-tyrosine phosphorylation [ISO]
- positive regulation of receptor activity [IMP]
- regulation of transcription, DNA-templated [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.8305 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID