BAIT
LGMN
AEP, AI746452, AU022324, Prsc1
legumain
GO Process (8)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- negative regulation of ERBB signaling pathway [IMP]
- negative regulation of multicellular organism growth [IMP]
- negative regulation of neuron apoptotic process [ISO]
- proteolysis [IDA, IMP, ISO]
- proteolysis involved in cellular protein catabolic process [IMP]
- receptor catabolic process [IMP]
- renal system process [IMP]
- response to acidic pH [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
C1QC
AI385742, C1qg, Ciqc, RP23-357K18.1
complement component 1, q subcomponent, C chain
GO Process (2)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.771 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID