BAIT
CTR9
AA409336, Sh2bp1, Tsbp, Tsp, mKIAA0155
Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
GO Process (18)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- JAK-STAT cascade [IMP]
- blastocyst growth [IGI, IMP]
- cellular response to lipopolysaccharide [IDA]
- endodermal cell fate commitment [IMP]
- histone H2B ubiquitination [ISO]
- histone H3-K4 trimethylation [IMP, ISO]
- histone monoubiquitination [ISO]
- inner cell mass cell differentiation [IMP]
- interleukin-6-mediated signaling pathway [IMP]
- negative regulation of myeloid cell differentiation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of histone H3-K4 methylation [IMP, ISO]
- positive regulation of histone H3-K79 methylation [ISO]
- positive regulation of transcription elongation from RNA polymerase II promoter [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- regulation of genetic imprinting [IMP]
- stem cell maintenance [IMP, ISO]
- trophectodermal cell differentiation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CACNA2D2
Cacna2d, a2d2, du, mKIAA0558, td, torpid
calcium channel, voltage-dependent, alpha 2/delta subunit 2
GO Process (8)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- calcium ion transmembrane transport [ISO]
- calcium ion transport [IC, ISO]
- muscle fiber development [IMP]
- neuromuscular junction development [IMP]
- positive regulation of organ growth [IMP]
- regulation of ion transmembrane transport [ISO]
- regulation of multicellular organism growth [IMP]
- rhythmic synaptic transmission [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.972 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID