BAIT
CACNB2
AW060387, CAB2, Cavbeta2, Cchb2, RP23-56A7.2
calcium channel, voltage-dependent, beta 2 subunit
GO Process (8)
GO Function (7)
GO Component (1)
Gene Ontology Biological Process
- calcium ion import [ISO]
- calcium ion transmembrane transport [ISO]
- neuromuscular junction development [IBA]
- positive regulation of calcium ion transport [ISO]
- regulation of ion transmembrane transport [ISO]
- regulation of voltage-gated calcium channel activity [IBA]
- synaptic transmission [IMP]
- visual perception [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CACNB4
3110038O15Rik, Cchb4, lh, RP23-435G20.4
calcium channel, voltage-dependent, beta 4 subunit
GO Process (22)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- Peyer's patch development [IMP]
- T cell differentiation [IMP]
- T cell receptor signaling pathway [IMP]
- adult walking behavior [IMP]
- cAMP metabolic process [IMP]
- calcium ion transmembrane transport [IMP, ISO]
- calcium ion transport [IMP, ISO]
- cellular calcium ion homeostasis [IMP]
- detection of light stimulus involved in visual perception [IMP]
- gamma-aminobutyric acid secretion [IMP]
- gamma-aminobutyric acid signaling pathway [IMP]
- muscle fiber development [IMP]
- neurological system process [IMP]
- neuromuscular junction development [IMP]
- neuronal action potential propagation [IMP]
- regulation of ion transmembrane transport [IMP]
- regulation of membrane potential [IMP]
- regulation of voltage-gated calcium channel activity [IBA, ISO]
- spleen development [IMP]
- synaptic transmission, GABAergic [IMP]
- synaptic transmission, glutamatergic [IMP]
- thymus development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.742 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID