BAIT
ALOX5
5-LO, 5-LOX, 5LO, 5LX, AI850497, F730011J02
arachidonate 5-lipoxygenase
GO Process (10)
GO Function (3)
GO Component (10)
Gene Ontology Biological Process
- acute inflammatory response [ISO]
- arachidonic acid metabolic process [ISO]
- inflammatory response [IMP]
- leukotriene biosynthetic process [IDA, IMP, ISO]
- leukotriene metabolic process [IMP]
- leukotriene production involved in inflammatory response [IMP]
- lipoxygenase pathway [ISO]
- oxidation-reduction process [ISO]
- positive regulation of vasoconstriction [ISO]
- sensory perception of pain [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CAMK2G
Camkg
calcium/calmodulin-dependent protein kinase II gamma
GO Process (7)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.952 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID