BAIT
NCOA2
D1Ertd433e, GRIP-1, Grip1, KAT13C, NCoA-2, SRC-2, TIF2, bHLHe75
nuclear receptor coactivator 2
GO Process (10)
GO Function (18)
GO Component (10)
Gene Ontology Biological Process
- cellular response to hormone stimulus [IBA]
- intracellular receptor signaling pathway [IBA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of female receptivity [ISO]
- positive regulation of glucocorticoid receptor signaling pathway [ISO]
- positive regulation of receptor activity [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IGI, ISO]
- regulation of glucose metabolic process [IMP]
- regulation of transcription, DNA-templated [IDA]
Gene Ontology Molecular Function- DNA polymerase binding [ISO]
- PDZ domain binding [ISO]
- chromatin binding [IDA]
- estrogen receptor binding [ISO]
- glucocorticoid receptor binding [ISO]
- ligand-dependent nuclear receptor binding [IBA, ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [IDA, ISO]
- nuclear hormone receptor binding [IBA, ISO]
- progesterone receptor binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- receptor binding [IDA]
- retinoic acid receptor binding [ISO]
- retinoid X receptor binding [ISO]
- thyroid hormone receptor binding [ISO]
- thyroid hormone receptor coactivator activity [IDA]
- transcription coactivator activity [IDA, IGI]
- transcription factor binding [IPI]
- DNA polymerase binding [ISO]
- PDZ domain binding [ISO]
- chromatin binding [IDA]
- estrogen receptor binding [ISO]
- glucocorticoid receptor binding [ISO]
- ligand-dependent nuclear receptor binding [IBA, ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [IDA, ISO]
- nuclear hormone receptor binding [IBA, ISO]
- progesterone receptor binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- receptor binding [IDA]
- retinoic acid receptor binding [ISO]
- retinoid X receptor binding [ISO]
- thyroid hormone receptor binding [ISO]
- thyroid hormone receptor coactivator activity [IDA]
- transcription coactivator activity [IDA, IGI]
- transcription factor binding [IPI]
Gene Ontology Cellular Component
Mus musculus
PREY
CC2D1A
BC016188, Freud-1, Tape
coiled-coil and C2 domain containing 1A
GO Process (4)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.951 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID