BAIT
CNOT1
6030411K04Rik, AA815922, D830048B13
CCR4-NOT transcription complex, subunit 1
GO Process (9)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- RNA phosphodiester bond hydrolysis, exonucleolytic [ISO]
- negative regulation of intracellular estrogen receptor signaling pathway [ISO]
- negative regulation of retinoic acid receptor signaling pathway [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of cytoplasmic mRNA processing body assembly [ISO]
- positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [ISO]
- positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [ISO]
- regulation of stem cell maintenance [IMP, ISO]
- trophectodermal cell differentiation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
COPA
AU040324, xenin
coatomer protein complex subunit alpha
GO Process (1)
GO Function (0)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.93 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID