BAIT
RPLP0
36B4, Arbp, L10E
ribosomal protein, large, P0
GO Process (1)
GO Function (1)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CTSH
AL022844
cathepsin H
GO Process (22)
GO Function (13)
GO Component (8)
Gene Ontology Biological Process
- ERK1 and ERK2 cascade [ISO]
- T cell mediated cytotoxicity [IGI]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IGI, ISO]
- apoptotic process [IGI]
- bradykinin catabolic process [ISO]
- dichotomous subdivision of terminal units involved in lung branching [IMP]
- immune response-regulating signaling pathway [ISO]
- membrane protein proteolysis [IMP, ISO]
- negative regulation of apoptotic process [IMP]
- neuropeptide catabolic process [ISO]
- positive regulation of angiogenesis [IMP]
- positive regulation of apoptotic signaling pathway [IGI]
- positive regulation of cell migration [ISO]
- positive regulation of cell proliferation [IMP]
- positive regulation of epithelial cell migration [IMP]
- positive regulation of gene expression [ISO]
- positive regulation of peptidase activity [IGI, ISO]
- protein destabilization [IMP, ISO]
- proteolysis [IDA, IMP, ISO]
- response to retinoic acid [IDA]
- surfactant homeostasis [ISO]
- zymogen activation [IMP, ISO]
Gene Ontology Molecular Function- HLA-A specific activating MHC class I receptor activity [ISO]
- aminopeptidase activity [ISO]
- cysteine-type endopeptidase activator activity involved in apoptotic process [IGI, ISO]
- cysteine-type endopeptidase activity [IDA, ISO]
- cysteine-type peptidase activity [ISO]
- endopeptidase activity [IMP, ISO]
- kininogen binding [ISO]
- peptidase activator activity involved in apoptotic process [IGI]
- peptidase activity [ISO]
- protein complex binding [ISO]
- protein self-association [ISO]
- serine-type endopeptidase activity [IMP]
- thyroid hormone binding [ISO]
- HLA-A specific activating MHC class I receptor activity [ISO]
- aminopeptidase activity [ISO]
- cysteine-type endopeptidase activator activity involved in apoptotic process [IGI, ISO]
- cysteine-type endopeptidase activity [IDA, ISO]
- cysteine-type peptidase activity [ISO]
- endopeptidase activity [IMP, ISO]
- kininogen binding [ISO]
- peptidase activator activity involved in apoptotic process [IGI]
- peptidase activity [ISO]
- protein complex binding [ISO]
- protein self-association [ISO]
- serine-type endopeptidase activity [IMP]
- thyroid hormone binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.684 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID