BAIT
FOS
D12Rfj1, c-fos, cFos
FBJ osteosarcoma oncogene
GO Process (14)
GO Function (13)
GO Component (5)
Gene Ontology Biological Process
- SMAD protein signal transduction [ISO]
- cellular response to calcium ion [IDA]
- cellular response to extracellular stimulus [IMP]
- cellular response to reactive oxygen species [ISO]
- nervous system development [IMP]
- positive regulation of osteoclast differentiation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of transcription, DNA-templated [IDA, IMP]
- response to drug [IDA]
- response to muscle stretch [IDA]
- skeletal muscle cell differentiation [IMP]
- transcription from RNA polymerase II promoter [IMP, ISO]
- transforming growth factor beta receptor signaling pathway [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- R-SMAD binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IMP]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- chromatin binding [IDA]
- double-stranded DNA binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA, IMP, ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [ISO]
- DNA binding [IDA, ISO]
- R-SMAD binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IMP]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- chromatin binding [IDA]
- double-stranded DNA binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA, IMP, ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
DEAF1
AU042387, C230009B13Rik, NUDR
deformed epidermal autoregulatory factor 1 (Drosophila)
GO Process (10)
GO Function (0)
GO Component (5)
Gene Ontology Biological Process
- behavioral fear response [IMP]
- embryonic skeletal system development [IMP]
- negative regulation of transcription, DNA-templated [ISO]
- neural tube closure [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of mammary gland epithelial cell proliferation [IMP, ISO]
- regulation of transcription from RNA polymerase II promoter [IDA]
- transcription from RNA polymerase II promoter [IDA]
- visual learning [IMP]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.752 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID