BAIT
FMNL2
5430425K04Rik, Man, RP23-282A22.1
formin-like 2
GO Process (3)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Mus musculus
PREY
DIAP1
D18Wsu154e, Dia1, Diaph1, Drf1, mKIAA4062, p140mDia
diaphanous homolog 1 (Drosophila)
GO Process (10)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
- actin cytoskeleton organization [IDA]
- actin filament polymerization [IDA]
- cellular response to histamine [ISO]
- cytoskeleton organization [ISO]
- neuron projection development [IDA]
- positive regulation of cell migration [ISO]
- protein localization to microtubule [ISO]
- regulation of cell shape [ISO]
- regulation of microtubule-based process [ISO]
- regulation of release of sequestered calcium ion into cytosol [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.906 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID