BAIT
DROSHA
1110013A17Rik, AI874853, Etohi2, Rn3, Rnasen
drosha, ribonuclease type III
GO Process (9)
GO Function (5)
GO Component (0)
Gene Ontology Biological Process
- RNA phosphodiester bond hydrolysis [ISO]
- RNA phosphodiester bond hydrolysis, endonucleolytic [IDA, ISO]
- defense response to Gram-negative bacterium [ISO]
- defense response to Gram-positive bacterium [ISO]
- miRNA metabolic process [IMP]
- pre-miRNA processing [IDA]
- primary miRNA processing [ISO]
- regulation of gene expression [IMP]
- regulation of miRNA metabolic process [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
ELF1
Elf-1, Sts1, mElf-1, p70
E74-like factor 1
GO Process (8)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- cell differentiation [IBA]
- negative regulation of T cell receptor signaling pathway [IGI]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP, ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of cytokine production [IGI]
- regulation of transcription from RNA polymerase II promoter [IBA]
- regulation of transcription, DNA-templated [ISO]
- transcription from RNA polymerase II promoter [IMP]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IMP, ISO]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IBA]
- sequence-specific DNA binding transcription factor activity [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IMP, ISO]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IBA]
- sequence-specific DNA binding transcription factor activity [ISO]
Gene Ontology Cellular Component
- nucleoplasm [ISO]
- nucleus [IDA, ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.795 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID