BAIT
FES
AI586313, BB137047, FPS, c-fes
feline sarcoma oncogene
GO Process (22)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
- cell adhesion [IBA]
- cell differentiation [IBA]
- cell migration [IBA]
- centrosome organization [IMP]
- chemotaxis [IBA]
- epidermal growth factor receptor signaling pathway [IBA]
- innate immune response [IBA]
- microtubule bundle formation [IDA]
- peptidyl-tyrosine autophosphorylation [IBA]
- peptidyl-tyrosine phosphorylation [ISO]
- positive regulation of actin cytoskeleton reorganization [ISO]
- positive regulation of microtubule polymerization [ISO]
- positive regulation of myeloid cell differentiation [ISO]
- positive regulation of neuron projection development [ISO]
- protein autophosphorylation [ISO]
- protein phosphorylation [IDA]
- regulation of cell adhesion [ISO]
- regulation of cell differentiation [ISO]
- regulation of cell motility [ISO]
- regulation of cell proliferation [IBA, ISO]
- regulation of cell shape [ISO]
- regulation of mast cell degranulation [IBA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ERBB3
C76256, Erbb-3, Erbb3r, Her3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
GO Process (18)
GO Function (8)
GO Component (7)
Gene Ontology Biological Process
- Schwann cell differentiation [IMP]
- cranial nerve development [IMP]
- endocardial cushion development [IMP]
- epidermal growth factor receptor signaling pathway [ISO]
- extrinsic apoptotic signaling pathway in absence of ligand [ISO]
- negative regulation of cell adhesion [ISO]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of secretion [ISO]
- negative regulation of signal transduction [ISO]
- neuron apoptotic process [ISO]
- peripheral nervous system development [IMP]
- phosphatidylinositol 3-kinase signaling [ISO]
- positive regulation of calcineurin-NFAT signaling cascade [IGI]
- positive regulation of glucose import [ISO]
- positive regulation of protein tyrosine kinase activity [ISO]
- regulation of cell proliferation [ISO]
- signal transduction [ISO]
- transmembrane receptor protein tyrosine kinase signaling pathway [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.993 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID