BAIT
ACTN3
actinin alpha 3
GO Process (1)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
FBP1
Fbp-2, Fbp2, Fbp3
fructose bisphosphatase 1
GO Process (11)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- carbohydrate metabolic process [ISO]
- cellular response to drug [ISO]
- cellular response to magnesium ion [ISO]
- dephosphorylation [ISO]
- fructose 6-phosphate metabolic process [ISO]
- gluconeogenesis [ISO]
- negative regulation of Ras protein signal transduction [ISO]
- negative regulation of cell growth [ISO]
- negative regulation of glycolytic process [ISO]
- protein homotetramerization [ISO]
- regulation of gluconeogenesis [ISO]
Gene Ontology Molecular Function
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.921 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID