BAIT
EPHA8
AW047546, Eek, Hek3, mKIAA1459, RP23-357K18.4
Eph receptor A8
GO Process (11)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- axon guidance [IMP]
- ephrin receptor signaling pathway [IDA]
- neuron projection development [IDA]
- neuron remodeling [IDA]
- peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of MAPK cascade [IDA]
- positive regulation of phosphatidylinositol 3-kinase activity [IDA]
- protein autophosphorylation [IDA]
- regulation of cell adhesion [IDA]
- regulation of cell adhesion mediated by integrin [IDA]
- substrate-dependent cell migration [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
FES
AI586313, BB137047, FPS, c-fes
feline sarcoma oncogene
GO Process (22)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
- cell adhesion [IBA]
- cell differentiation [IBA]
- cell migration [IBA]
- centrosome organization [IMP]
- chemotaxis [IBA]
- epidermal growth factor receptor signaling pathway [IBA]
- innate immune response [IBA]
- microtubule bundle formation [IDA]
- peptidyl-tyrosine autophosphorylation [IBA]
- peptidyl-tyrosine phosphorylation [ISO]
- positive regulation of actin cytoskeleton reorganization [ISO]
- positive regulation of microtubule polymerization [ISO]
- positive regulation of myeloid cell differentiation [ISO]
- positive regulation of neuron projection development [ISO]
- protein autophosphorylation [ISO]
- protein phosphorylation [IDA]
- regulation of cell adhesion [ISO]
- regulation of cell differentiation [ISO]
- regulation of cell motility [ISO]
- regulation of cell proliferation [IBA, ISO]
- regulation of cell shape [ISO]
- regulation of mast cell degranulation [IBA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.719 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID