BAIT
ARHGAP35
6430596G11Rik, AI841135, Grlf1, mKIAA1722, p190A, p190RhoGAP
Rho GTPase activating protein 35
GO Process (9)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- camera-type eye development [IMP]
- forebrain development [IMP]
- integrin-mediated signaling pathway [TAS]
- negative regulation of Rho protein signal transduction [IDA, IGI]
- negative regulation of vascular permeability [IMP]
- neural tube closure [IMP]
- positive regulation of GTPase activity [TAS]
- positive regulation of neuron projection development [IGI]
- regulation of cell shape [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
FGD4
9030023J02Rik, 9330209B17Rik, Frabp, ZFYVE6
FYVE, RhoGEF and PH domain containing 4
GO Process (4)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.808 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID