BAIT
ASTN1
Astn, GC14, mKIAA0289
astrotactin 1
GO Process (5)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
GAS6
Gas-6
growth arrest specific 6
GO Process (59)
GO Function (8)
GO Component (4)
Gene Ontology Biological Process
- B cell chemotaxis [ISO]
- activation of protein kinase B activity [ISO]
- apoptotic cell clearance [IDA, ISO]
- blood coagulation [IMP]
- calcium ion transmembrane transport [ISO]
- cell-substrate adhesion [IMP]
- cellular response to drug [ISO]
- cellular response to glucose stimulus [ISO]
- cellular response to growth factor stimulus [IDA, IMP]
- cellular response to interferon-alpha [ISO]
- cellular response to starvation [IDA]
- cellular response to vitamin K [ISO]
- enzyme linked receptor protein signaling pathway [IGI]
- fusion of virus membrane with host plasma membrane [ISO]
- hematopoietic stem cell migration to bone marrow [ISO]
- macrophage cytokine production [IMP]
- negative regulation of apoptotic process [IDA, IGI, IMP, ISO]
- negative regulation of biomineral tissue development [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of dendritic cell apoptotic process [ISO]
- negative regulation of endothelial cell apoptotic process [ISO]
- negative regulation of fibroblast apoptotic process [ISO]
- negative regulation of interferon-gamma production [ISO]
- negative regulation of interleukin-1 secretion [ISO]
- negative regulation of interleukin-6 production [ISO]
- negative regulation of interleukin-6 secretion [ISO]
- negative regulation of oligodendrocyte apoptotic process [ISO]
- negative regulation of protein import into nucleus, translocation [ISO]
- negative regulation of sequence-specific DNA binding transcription factor activity [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- negative regulation of tumor necrosis factor production [ISO]
- negative regulation of tumor necrosis factor-mediated signaling pathway [ISO]
- neuron migration [IGI]
- peptidyl-serine phosphorylation [ISO]
- phagocytosis [ISO]
- positive regulation of ERK1 and ERK2 cascade [ISO]
- positive regulation of TOR signaling [ISO]
- positive regulation of cytokine-mediated signaling pathway [ISO]
- positive regulation of dendritic cell chemotaxis [ISO]
- positive regulation of fibroblast proliferation [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of glomerular filtration [ISO]
- positive regulation of natural killer cell differentiation [ISO]
- positive regulation of peptidyl-serine phosphorylation [ISO]
- positive regulation of phagocytosis [ISO]
- positive regulation of protein export from nucleus [ISO]
- positive regulation of protein kinase B signaling [ISO]
- positive regulation of protein kinase activity [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of protein tyrosine kinase activity [ISO]
- positive regulation of receptor activity [IDA]
- protein kinase B signaling [IGI, IMP, ISO]
- protein phosphorylation [ISO]
- protein targeting to plasma membrane [ISO]
- receptor-mediated virion attachment to host cell [ISO]
- regulation of ion transmembrane transport [ISO]
- signal transduction [IDA, ISO]
- viral entry into host cell [ISO]
- viral genome replication [ISO]
Gene Ontology Molecular Function- binding, bridging [ISO]
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process [ISO]
- phosphatidylserine binding [ISO]
- protein tyrosine kinase activator activity [ISO]
- receptor agonist activity [IDA, ISO]
- receptor binding [ISO]
- receptor tyrosine kinase binding [ISO]
- voltage-gated calcium channel activity [ISO]
- binding, bridging [ISO]
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process [ISO]
- phosphatidylserine binding [ISO]
- protein tyrosine kinase activator activity [ISO]
- receptor agonist activity [IDA, ISO]
- receptor binding [ISO]
- receptor tyrosine kinase binding [ISO]
- voltage-gated calcium channel activity [ISO]
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.71 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID