BAIT
LAMA5
AA408760, AA408762, AI853660, [a]5, laminin-511, mKIAA0533, RP23-16P3.3
laminin, alpha 5
GO Process (17)
GO Function (2)
GO Component (9)
Gene Ontology Biological Process
- branching involved in salivary gland morphogenesis [IMP]
- branching involved in ureteric bud morphogenesis [IMP]
- branching morphogenesis of an epithelial tube [IMP]
- cell migration [ISO]
- cilium assembly [IMP]
- establishment of protein localization to plasma membrane [IMP]
- hair follicle development [IMP]
- integrin-mediated signaling pathway [ISO]
- lung development [IMP]
- morphogenesis of a polarized epithelium [IMP]
- morphogenesis of embryonic epithelium [IMP]
- muscle organ development [IMP]
- neural crest cell migration [IMP]
- odontogenesis of dentin-containing tooth [IMP]
- organ morphogenesis [IMP]
- regulation of cell proliferation [IMP]
- substrate adhesion-dependent cell spreading [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ITGA6
5033401O05Rik, AI115430, Cd49f, VLA-6, RP23-5K9.4
integrin alpha 6
GO Process (20)
GO Function (3)
GO Component (13)
Gene Ontology Biological Process
- amelogenesis [ISO]
- brown fat cell differentiation [IDA]
- cell adhesion mediated by integrin [IDA]
- cell-matrix adhesion [IMP]
- cell-substrate adhesion [ISO]
- cellular response to extracellular stimulus [IDA]
- digestive tract development [ISO]
- filopodium assembly [IMP]
- leukocyte migration [IGI, IMP]
- nail development [ISO]
- negative regulation of extrinsic apoptotic signaling pathway [ISO]
- odontogenesis of dentin-containing tooth [IMP]
- positive regulation of apoptotic process [ISO]
- positive regulation of cell-cell adhesion [IDA]
- positive regulation of cell-substrate adhesion [ISO]
- positive regulation of phosphorylation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- renal system development [ISO]
- single organismal cell-cell adhesion [ISO]
- skin development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- basal part of cell [IDA]
- basal plasma membrane [IDA]
- basement membrane [IDA]
- basolateral plasma membrane [IDA]
- cell surface [IDA, ISO]
- cell-cell adherens junction [ISO]
- external side of plasma membrane [IDA]
- filopodium [ISO]
- focal adhesion [ISO]
- hemidesmosome [IDA]
- integrin alpha6-beta4 complex [ISO]
- integrin complex [IDA]
- plasma membrane [IDA, ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.968 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID