BAIT
ITGB2
2E6, AI528527, Cd18, LAD, LCAMB, Lfa1, MF17
integrin beta 2
GO Process (18)
GO Function (7)
GO Component (8)
Gene Ontology Biological Process
- activated T cell proliferation [IMP]
- cell adhesion [IGI, IMP]
- cell-matrix adhesion [ISO]
- cellular extravasation [IMP, ISO]
- endothelial cell migration [ISO]
- heterotypic cell-cell adhesion [ISO]
- integrin-mediated signaling pathway [IDA]
- leukocyte cell-cell adhesion [ISO]
- leukocyte migration involved in inflammatory response [ISO]
- natural killer cell activation [ISO]
- neutrophil chemotaxis [IMP, ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of angiogenesis [ISO]
- positive regulation of nitric oxide biosynthetic process [ISO]
- receptor clustering [ISO]
- regulation of peptidyl-tyrosine phosphorylation [ISO]
- signal transduction [ISO]
- single organismal cell-cell adhesion [IGI, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ITGAX
AI449405, Cd11c, Cr4, N418
integrin alpha X
GO Process (3)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.829 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID