BAIT
INPPL1
51C, SHIP2
inositol polyphosphate phosphatase-like 1
GO Process (19)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- actin filament organization [ISO]
- cellular lipid metabolic process [IMP]
- dephosphorylation [ISO]
- endochondral ossification [ISO]
- endocytosis [ISO]
- glucose metabolic process [IMP]
- inositol trisphosphate metabolic process [ISO]
- negative regulation of DNA replication [ISO]
- negative regulation of MAP kinase activity [ISO]
- negative regulation of cell proliferation [IDA]
- negative regulation of gene expression [IMP]
- negative regulation of insulin receptor signaling pathway [ISO]
- negative regulation of insulin-like growth factor receptor signaling pathway [ISO]
- negative regulation of neuron projection development [ISO]
- negative regulation of platelet-derived growth factor receptor signaling pathway [ISO]
- phosphatidylinositol biosynthetic process [IMP]
- post-embryonic development [IMP]
- response to insulin [IMP]
- ruffle assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
KRT5
3300001P10Rik, AW146334, CK5, K5, Krt2-5, Tfip8
keratin 5
GO Process (0)
GO Function (2)
GO Component (8)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.799 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID