BAIT
D630045J12RIK
Kiaa1549, mKIAA1549
RIKEN cDNA D630045J12 gene
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY
LATS1
AW208599
large tumor suppressor
GO Process (13)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [ISO]
- cellular protein localization [IGI]
- cytoplasmic sequestering of protein [ISO]
- hippo signaling [IGI, ISO]
- hormone-mediated signaling pathway [IDA]
- keratinocyte differentiation [IGI]
- negative regulation of canonical Wnt signaling pathway [ISO]
- negative regulation of cyclin-dependent protein serine/threonine kinase activity [ISO]
- positive regulation of peptidyl-serine phosphorylation [ISO]
- protein phosphorylation [ISO]
- regulation of actin filament polymerization [ISO]
- regulation of protein complex assembly [ISO]
- sister chromatid segregation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.797 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID