BAIT
RAB10
AW107754
RAB10, member RAS oncogene family
GO Process (17)
GO Function (5)
GO Component (16)
Gene Ontology Biological Process
- GTP catabolic process [IBA, ISO]
- Golgi to plasma membrane transport [ISO]
- Rab protein signal transduction [IBA]
- antigen processing and presentation [ISO]
- axonogenesis [ISO]
- cellular response to insulin stimulus [IMP]
- endoplasmic reticulum tubular network organization [ISO]
- endosomal transport [ISO]
- establishment of neuroblast polarity [ISO]
- establishment of protein localization to endoplasmic reticulum membrane [ISO]
- establishment of protein localization to membrane [ISO]
- intracellular protein transport [TAS]
- protein localization to plasma membrane [IMP]
- protein secretion [IBA]
- regulation of exocytosis [IBA]
- vesicle docking involved in exocytosis [IBA]
- vesicle-mediated transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA, ISO]
- cell [TAS]
- endoplasmic reticulum membrane [ISO]
- endoplasmic reticulum tubular network [ISO]
- endosome [ISO]
- endosome membrane [IBA]
- extracellular vesicular exosome [ISO]
- focal adhesion [ISO]
- insulin-responsive compartment [IBA, ISO]
- intracellular [TAS]
- membrane [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [ISO]
- primary cilium [IDA, ISO]
- recycling endosome [ISO]
- trans-Golgi network [ISO]
Mus musculus
PREY
MICAL1
MICAL, MICAL-1, Nical
microtubule associated monooxygenase, calponin and LIM domain containing 1
GO Process (6)
GO Function (7)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function- FAD binding [ISO]
- Rab GTPase binding [IPI]
- SH3 domain binding [ISO]
- actin binding [IDA, ISO]
- monooxygenase activity [IMP]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [IDA, ISO]
- protein binding [IPI]
- FAD binding [ISO]
- Rab GTPase binding [IPI]
- SH3 domain binding [ISO]
- actin binding [IDA, ISO]
- monooxygenase activity [IMP]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [IDA, ISO]
- protein binding [IPI]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.77 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID