BAIT
MYH14
2400004E04Rik, II-C, NHMCII, NMHC II-C
myosin, heavy polypeptide 14
GO Process (9)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- ATP catabolic process [IDA, ISO]
- actin filament-based movement [IDA]
- actomyosin structure organization [ISO]
- mitochondrion morphogenesis [ISO]
- neuronal action potential [ISO]
- sensory perception of sound [ISO]
- skeletal muscle contraction [ISO]
- skeletal muscle tissue development [ISO]
- vocalization behavior [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
MYO5A
9630007J19Rik, AI413174, AI661011, Dbv, MVa, Myo5, MyoVA, Sev-1, d, d-120J, flail, flr, RP24-189I2.1
myosin VA
GO Process (29)
GO Function (15)
GO Component (29)
Gene Ontology Biological Process
- actin filament-based movement [IDA, ISO]
- anagen [IMP]
- cellular response to insulin stimulus [IMP]
- developmental pigmentation [IMP]
- endoplasmic reticulum localization [IMP]
- exocytosis [IMP]
- insulin secretion [IMP]
- locomotion involved in locomotory behavior [IMP]
- long-chain fatty acid biosynthetic process [IMP]
- melanin biosynthetic process [IMP]
- melanin metabolic process [IMP]
- melanocyte differentiation [IMP]
- melanosome localization [IMP]
- melanosome transport [IDA, IMP]
- metabolic process [ISO]
- myelination [IMP]
- neuromuscular process controlling balance [IMP]
- odontogenesis [IDA]
- pigmentation [IMP, ISA]
- post-Golgi vesicle-mediated transport [ISO]
- protein localization to plasma membrane [IMP]
- regulation of exocytosis [ISO]
- regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [IMP]
- secretory granule localization [IMP, ISO]
- synapse organization [IMP]
- synaptic transmission [IMP]
- vesicle transport along actin filament [ISO, TAS]
- vesicle-mediated transport [IMP]
- visual perception [IMP]
Gene Ontology Molecular Function- ATP binding [ISO]
- ATP-dependent protein binding [ISO]
- Rab GTPase binding [IPI, ISO]
- SNARE binding [ISO]
- actin binding [IDA]
- calcium ion binding [IDA]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- microfilament motor activity [IDA, ISO]
- motor activity [IDA, ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein dimerization activity [ISO]
- protein heterodimerization activity [ISO]
- syntaxin-1 binding [ISO]
- ATP binding [ISO]
- ATP-dependent protein binding [ISO]
- Rab GTPase binding [IPI, ISO]
- SNARE binding [ISO]
- actin binding [IDA]
- calcium ion binding [IDA]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- microfilament motor activity [IDA, ISO]
- motor activity [IDA, ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein dimerization activity [ISO]
- protein heterodimerization activity [ISO]
- syntaxin-1 binding [ISO]
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- actin filament [ISO]
- actomyosin [IDA]
- actomyosin, myosin complex part [ISO]
- axon [ISO]
- cell [IMP]
- cytoplasm [IDA, ISO]
- cytosol [ISO]
- early endosome [ISO]
- endoplasmic reticulum [ISO]
- extracellular vesicular exosome [ISO]
- filopodium tip [ISO]
- insulin-responsive compartment [IDA]
- intermediate filament [IDA]
- late endosome [ISO]
- lysosome [ISO]
- melanosome [IDA]
- membrane [ISO]
- microtubule plus-end [IDA]
- myosin complex [IDA]
- neuron projection [ISO]
- neuronal cell body [IDA, ISO]
- peroxisome [ISO]
- photoreceptor outer segment [IDA]
- recycling endosome [ISO]
- ruffle [ISO]
- secretory granule [IDA, ISO]
- synaptic vesicle [ISO]
- vesicle [ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.814 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID