BAIT
SERPINE2
B230326M24Rik, PAI-1, PI-7, PI7, PN-1, Spi4
serine (or cysteine) peptidase inhibitor, clade E, member 2
GO Process (29)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- blood coagulation [IMP]
- cerebellar granular layer morphogenesis [IMP]
- dense core granule biogenesis [ISO]
- detection of mechanical stimulus involved in sensory perception [IMP]
- innervation [IMP]
- long-term synaptic potentiation [IMP]
- mating plug formation [IMP]
- negative regulation of blood coagulation [ISO]
- negative regulation of cell growth [IGI]
- negative regulation of cell proliferation [IGI]
- negative regulation of endopeptidase activity [IMP]
- negative regulation of peptidase activity [IMP]
- negative regulation of phosphatidylinositol 3-kinase signaling [IGI]
- negative regulation of plasminogen activation [IMP, ISO]
- negative regulation of platelet activation [IMP]
- negative regulation of platelet aggregation [IMP]
- negative regulation of protein catabolic process [IMP, ISO]
- negative regulation of protein processing [IC]
- negative regulation of proteolysis [ISO]
- negative regulation of smoothened signaling pathway [IGI]
- negative regulation of sodium ion transport [IGI, IMP]
- positive regulation of astrocyte differentiation [ISO]
- positive regulation of neuron projection development [ISO]
- regulation of synaptic transmission, glutamatergic [IMP]
- regulation of timing of cell differentiation [IMP]
- response to wounding [IMP]
- secretion by cell [IMP, ISO]
- secretory granule organization [IMP, ISO]
- seminal vesicle epithelium development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NCBP1
AU014645, AW538051, CBP80, RP23-13L18.1
nuclear cap binding protein subunit 1
GO Process (6)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.764 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID