BAIT
SAP30
30kDa
sin3 associated polypeptide
GO Process (4)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NCOR2
N-CoR, SMRT, SMRTe
nuclear receptor co-repressor 2
GO Process (13)
GO Function (14)
GO Component (8)
Gene Ontology Biological Process
- Type I pneumocyte differentiation [IGI, IMP]
- cell proliferation in forebrain [IMP]
- forebrain development [IMP]
- glucose homeostasis [IMP]
- heart morphogenesis [IGI, IMP]
- in utero embryonic development [IMP]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of protein deacetylation [IDA]
- regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter [ISO]
- telencephalon development [IMP]
- white fat cell differentiation [IMP]
Gene Ontology Molecular Function- DNA binding [IDA]
- Notch binding [ISO]
- RNA polymerase II regulatory region DNA binding [ISO]
- chromatin binding [IDA, ISO]
- glucocorticoid receptor binding [ISO]
- histone deacetylase binding [ISO]
- ligand-dependent nuclear receptor binding [ISO]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- retinoic acid receptor binding [ISO]
- retinoid X receptor binding [ISO]
- sequence-specific DNA binding [IDA]
- transcription corepressor activity [IDA, IGI, IMP, ISO]
- DNA binding [IDA]
- Notch binding [ISO]
- RNA polymerase II regulatory region DNA binding [ISO]
- chromatin binding [IDA, ISO]
- glucocorticoid receptor binding [ISO]
- histone deacetylase binding [ISO]
- ligand-dependent nuclear receptor binding [ISO]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- retinoic acid receptor binding [ISO]
- retinoid X receptor binding [ISO]
- sequence-specific DNA binding [IDA]
- transcription corepressor activity [IDA, IGI, IMP, ISO]
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.876 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID