BAIT
ADRBK1
Adrbk-1, Bark-1, GRK2, beta ARK, betaARK1
adrenergic receptor kinase, beta 1
GO Process (17)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IDA, ISO]
- cardiac muscle contraction [ISO]
- desensitization of G-protein coupled receptor protein signaling pathway [IGI, IMP, ISO]
- follicle-stimulating hormone signaling pathway [ISO]
- heart development [IMP]
- negative regulation of G-protein coupled receptor protein signaling pathway [ISO]
- negative regulation of striated muscle contraction [ISO]
- negative regulation of the force of heart contraction by chemical signal [ISO]
- peptidyl-serine phosphorylation [IDA]
- peptidyl-threonine phosphorylation [IDA]
- positive regulation of catecholamine secretion [ISO]
- protein phosphorylation [IDA, IMP, ISO]
- receptor internalization [ISO]
- regulation of the force of heart contraction [IGI]
- response to organic cyclic compound [ISO]
- response to oxidative stress [ISO]
- tachykinin receptor signaling pathway [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PDCL
1200011E13Rik, AW108059, PhLP1, RP23-464H12.4
phosducin-like
GO Process (4)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.889 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID