BAIT
HSD17B4
17-beta-HSD, 17[b]-HSD, 4, DBP, MFE-2, MFP2, MPF-2, Mfp-2, perMFE-2
hydroxysteroid (17-beta) dehydrogenase 4
GO Process (10)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- Sertoli cell development [IMP]
- androgen metabolic process [ISO]
- estrogen metabolic process [ISO]
- fatty acid beta-oxidation [IMP, ISO]
- medium-chain fatty-acyl-CoA metabolic process [ISO]
- metabolic process [ISO]
- osteoblast differentiation [ISO]
- oxidation-reduction process [ISO]
- very long-chain fatty acid metabolic process [IMP]
- very long-chain fatty-acyl-CoA metabolic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PEX14
Pex14p, R75137, RP23-121D17.1
peroxisomal biogenesis factor 14
GO Process (12)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- microtubule anchoring [ISO]
- negative regulation of protein binding [ISO]
- negative regulation of protein homotetramerization [ISO]
- negative regulation of sequence-specific DNA binding transcription factor activity [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- peroxisome organization [ISO]
- peroxisome transport along microtubule [ISO]
- protein complex assembly [ISO]
- protein homooligomerization [ISO]
- protein import into peroxisome matrix [ISO]
- protein import into peroxisome matrix, substrate release [ISO]
- protein import into peroxisome matrix, translocation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.928 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID