BAIT
SKIL
Skir, SnoN, sno
SKI-like
GO Process (16)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
- blastocyst formation [IMP]
- cell cycle arrest [IMP]
- lens fiber cell differentiation [IDA]
- lymphocyte homeostasis [IMP]
- negative regulation of cell differentiation [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI, ISO]
- negative regulation of transforming growth factor beta receptor signaling pathway [IMP, ISO]
- positive regulation of axonogenesis [ISO]
- positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [IMP]
- positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [IMP]
- protein heterotrimerization [ISO]
- protein homotrimerization [ISO]
- response to growth factor [ISO]
- skeletal muscle tissue development [ISO]
- transcription from RNA polymerase II promoter [ISO]
- transforming growth factor beta receptor signaling pathway [IGI]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- SMAD binding [IBA, ISO]
- chromatin binding [IDA]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [ISO]
- transcription corepressor activity [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- SMAD binding [IBA, ISO]
- chromatin binding [IDA]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [ISO]
- transcription corepressor activity [ISO]
Mus musculus
PREY
PLCD3
2610205J15Rik, mKIAA1964, RP23-358E19.2
phospholipase C, delta 3
GO Process (3)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.969 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID