BAIT
SEMA6A
9330158E07, A730020P05Rik, AI851735, Sema6A-1, Semaq, VIa, b2b997Clo
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
GO Process (7)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
PLXNA4
9330117B14, Plxa4, mKIAA1550
plexin A4
GO Process (15)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- anterior commissure morphogenesis [IMP]
- axon guidance [IMP]
- chemorepulsion of branchiomotor axon [IMP]
- cranial nerve morphogenesis [IMP]
- facial nerve morphogenesis [IMP]
- glossopharyngeal nerve morphogenesis [IMP]
- nervous system development [IGI]
- neuron projection morphogenesis [IMP]
- postganglionic parasympathetic nervous system development [IMP]
- regulation of axon extension involved in axon guidance [IMP]
- regulation of negative chemotaxis [IMP]
- semaphorin-plexin signaling pathway [IGI, IMP]
- sympathetic nervous system development [IMP]
- trigeminal nerve morphogenesis [IMP]
- vagus nerve morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.961 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
PLXNA4 SEMA6A | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | High | - | BioGRID | 2549878 |
Curated By
- BioGRID