BAIT
ABCB5
9230106F14Rik
ATP-binding cassette, sub-family B (MDR/TAP), member 5
GO Process (8)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [IBA]
- antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [IBA]
- antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [IBA]
- compound eye corneal lens development [IMP]
- positive regulation of antigen processing and presentation of peptide antigen via MHC class I [IBA]
- regulation of membrane potential [ISO]
- transmembrane transport [IBA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RPS27L
1810034D23Rik
ribosomal protein S27-like
GO Process (7)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
- DNA repair [ISO]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- cellular response to DNA damage stimulus [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [ISO]
- mitotic G1 DNA damage checkpoint [ISO]
- positive regulation of translation [ISO]
- translation [ISO]
Gene Ontology Molecular Function
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.768 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID