BAIT
FGF13
Fhf2, RP23-387L21.1
fibroblast growth factor 13
GO Process (14)
GO Function (5)
GO Component (11)
Gene Ontology Biological Process
- MAPK cascade [ISO]
- apoptotic process [IMP]
- cell proliferation [IMP]
- cerebral cortex cell migration [IMP]
- establishment of neuroblast polarity [IMP]
- hippocampus development [IMP]
- learning [IMP]
- memory [IMP]
- microtubule polymerization [IMP]
- negative regulation of collateral sprouting [IMP]
- negative regulation of microtubule depolymerization [IMP]
- neuron migration [IMP]
- positive regulation of protein kinase activity [ISO]
- protein localization to plasma membrane [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SCN8A
AI853486, C630029C19Rik, NaCh6, Nav1.6, dmu, med, mnd-2, mnd2, nmf2, nmf335, nmf58, nur14, seal
sodium channel, voltage-gated, type VIII, alpha
GO Process (12)
GO Function (3)
GO Component (10)
Gene Ontology Biological Process
- adult locomotory behavior [IMP]
- adult walking behavior [IMP]
- locomotory behavior [IMP]
- membrane depolarization during action potential [IBA]
- muscle organ development [IMP]
- neuromuscular process [IMP]
- neuronal action potential [IBA, ISO]
- regulation of ion transmembrane transport [NAS]
- response to toxic substance [IDA]
- sensory perception of sound [IMP]
- sodium ion transmembrane transport [ISO, NAS]
- sodium ion transport [ISO, NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.913 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID