BAIT
SLC22A1
Lx1, Oct1, Orct, Orct1
solute carrier family 22 (organic cation transporter), member 1
GO Process (13)
GO Function (9)
GO Component (2)
Gene Ontology Biological Process
- acetate ester transport [ISO]
- cation transmembrane transport [IDA, ISO]
- cation transport [IDA]
- dopamine transport [ISO]
- drug transmembrane transport [ISO]
- epinephrine transport [ISO]
- establishment or maintenance of transmembrane electrochemical gradient [ISO]
- monoamine transport [ISO]
- neurotransmitter transport [ISO]
- norepinephrine transport [ISO]
- organic cation transport [IDA, ISO]
- protein homooligomerization [ISO]
- quaternary ammonium group transport [ISO]
Gene Ontology Molecular Function- acetylcholine transmembrane transporter activity [ISO]
- dopamine transmembrane transporter activity [ISO]
- identical protein binding [ISO]
- monoamine transmembrane transporter activity [ISO]
- norepinephrine transmembrane transporter activity [ISO]
- organic cation transmembrane transporter activity [IDA, ISO]
- protein homodimerization activity [ISO]
- quaternary ammonium group transmembrane transporter activity [ISO]
- secondary active organic cation transmembrane transporter activity [ISO]
- acetylcholine transmembrane transporter activity [ISO]
- dopamine transmembrane transporter activity [ISO]
- identical protein binding [ISO]
- monoamine transmembrane transporter activity [ISO]
- norepinephrine transmembrane transporter activity [ISO]
- organic cation transmembrane transporter activity [IDA, ISO]
- protein homodimerization activity [ISO]
- quaternary ammonium group transmembrane transporter activity [ISO]
- secondary active organic cation transmembrane transporter activity [ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
SLC17A7
2900052E22Rik, AI851913, Vglut1
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
GO Process (11)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
- L-glutamate import [IDA, IGI, IMP]
- long-term memory [IMP]
- phosphate ion transmembrane transport [ISO]
- phosphate ion transport [ISO]
- regulation of excitatory postsynaptic membrane potential [IMP]
- sequestering of neurotransmitter [IMP]
- sodium ion transmembrane transport [ISO]
- sodium-dependent phosphate transport [ISO]
- synaptic transmission [IMP]
- synaptic transmission, glutamatergic [IMP]
- synaptic vesicle lumen acidification [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.929 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID