BAIT
PIK3CA
6330412C24Rik, caPI3K, p110, p110alpha
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
GO Process (13)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- glucose metabolic process [IMP]
- hypomethylation of CpG island [IDA]
- negative regulation of anoikis [ISO]
- negative regulation of fibroblast apoptotic process [IDA]
- negative regulation of neuron apoptotic process [IMP]
- phosphatidylinositol phosphorylation [IBA, ISO]
- phosphatidylinositol-3-phosphate biosynthetic process [ISO]
- positive regulation of peptidyl-serine phosphorylation [IDA]
- positive regulation of protein kinase activity [IDA]
- protein kinase B signaling [IMP]
- protein phosphorylation [IDA]
- regulation of genetic imprinting [IDA]
- regulation of multicellular organism growth [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SLC9A3R2
0610011L07Rik, 1200011K07Rik, 2010007A20Rik, E3karp, NHERF-2, Nherf2, Octs2, Sip-1, Sip1, Sryip1, Tka-1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
GO Process (3)
GO Function (9)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.753 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID