BAIT
SMARCC2
5930405J04Rik
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
GO Process (7)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- ATP-dependent chromatin remodeling [ISO]
- chromatin remodeling [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IGI]
- negative regulation of transcription, DNA-templated [ISO]
- nucleosome disassembly [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SRGAP3
AI452337, Arhgap14, D130026O08Rik, Gbi, MEGAP, WRP, mKIAA0411
SLIT-ROBO Rho GTPase activating protein 3
GO Process (2)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.818 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID